Gene

ndrg4

ID

ZDB-GENE-060512-226

Name

NDRG family member 4

Symbol

ndrg4 Nomenclature History

Previous Names

si:ch211-194m7.2 (1)
zgc:136766 (1)

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Involved in cardiac muscle cell proliferation; clustering of voltage-gated sodium channels; and heart looping. Predicted to localize to cytoplasm. Is expressed in basal plate midbrain region; cardiovascular system; nervous system; and spinal cord neural tube. Orthologous to human NDRG4 (NDRG family member 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

23 figures from 8 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

eu2445 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 12 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ndrg4 Human Ortholog

No data available

Associated With ndrg4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR004142	NDRG
Homologous_superfamily	IPR029058	Alpha/Beta hydrolase fold

Domain Details Per Protein

Protein	Length	Alpha/Beta hydrolase fold	NDRG
UniProtKB:A6XCT1 InterPro	339
UniProtKB:A0A8M2BA87 InterPro	429
UniProtKB:A0A8M2BA26 InterPro	413
UniProtKB:A0A8M2BA65 InterPro	445
UniProtKB:Q1JPS5 InterPro	352
UniProtKB:A0A8M9P6H2 InterPro	384
UniProtKB:A0A0R4ICQ1 InterPro	352
UniProtKB:A0A8M2BA44 InterPro	458

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	ndrg4-202 (1) Ensembl	Havana	712 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ndrg4-201 (1) Ensembl	Havana	6116 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ndrg4-203 (1) Ensembl	Havana	628 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ndrg4-204 (1) Ensembl	Havana	1800 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ndrg4-205 (1) Ensembl	Havana	763 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations