ZFIN is now using GRCz12tu for Genomic Data
Gene
edn2
- ID
- ZDB-GENE-060503-774
- Name
- endothelin 2
- Symbol
- edn2 Nomenclature History
- Previous Names
-
- si:ch211-202b2.2
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable endothelin B receptor binding activity and hormone activity. Predicted to be involved in several processes, including positive regulation of smooth muscle contraction; regulation of systemic arterial blood pressure by endothelin; and vein smooth muscle contraction. Predicted to be active in extracellular region. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human EDN2 (endothelin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Goldman et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Endothelin | Endothelin-like toxin | Endothelin-like toxin, conserved site |
|---|---|---|---|---|---|
| UniProtKB:Q1MT02 | InterPro | 164 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers