Gene
rspo2
- ID
- ZDB-GENE-060503-667
- Name
- R-spondin 2
- Symbol
- rspo2 Nomenclature History
- Previous Names
-
- si:ch211-149p10.1
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Involved in fin development and skeletal system development. Is expressed in several structures, including brain; fin; forebrain midbrain boundary neural rod; pectoral fin bud; and posterior lateral line ganglion. Orthologous to human RSPO2 (R-spondin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| tetraamelia syndrome 2 | Alliance | Tetraamelia syndrome 2 | 618021 |
| ?Humerofemoral hypoplasia with radiotibial ray deficiency | 618022 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR043601 | R-spondin, Fu-CRD domain |
| Domain | IPR044004 | Spondin-like TSP1 domain |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily |
| Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
| Repeat | IPR006212 | Furin-like repeat |
Domain Details Per Protein
| Protein | Length | Furin-like repeat | Growth factor receptor cysteine-rich domain superfamily | R-spondin, Fu-CRD domain | Spondin-like TSP1 domain | Thrombospondin type-1 (TSP1) repeat | Thrombospondin type-1 (TSP1) repeat superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F1Q5C9
|
Interactions and Pathways
No data available
Plasmids
No data available