jarid2b

ID

ZDB-GENE-060503-246

Name

jumonji and AT-rich interaction domain containing 2b

Symbol

jarid2b Nomenclature History

Previous Names

si:dkey-211c3.1

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable chromatin binding activity and histone demethylase activity. Predicted to contribute to histone H3K27 methyltransferase activity. Predicted to be involved in chromatin remodeling; regulation of gene expression; and stem cell differentiation. Predicted to act upstream of or within cell differentiation and chromatin organization. Predicted to be part of ESC/E(Z) complex. Predicted to be active in chromatin and nucleus. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human JARID2 (jumonji and AT-rich interaction domain containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With jarid2b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Developmental delay with variable intellectual disability and dysmorphic facies	620098

Associated With jarid2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001606	ARID DNA-binding domain
Domain	IPR003347	JmjC domain
Domain	IPR003349	JmjN domain
Domain	IPR004198	Zinc finger, C5HC2-type
Homologous_superfamily	IPR036431	ARID DNA-binding domain superfamily