ZFIN is now using GRCz12tu for Genomic Data
Gene
vcam1a
- ID
- ZDB-GENE-060503-172
- Name
- vascular cell adhesion molecule 1a
- Symbol
- vcam1a Nomenclature History
- Previous Names
-
- si:dkey-60b12.4
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Acts upstream of or within lymphangiogenesis. Human ortholog(s) of this gene implicated in gastrointestinal system disease. Orthologous to human VCAM1 (vascular cell adhesion molecule 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-vcam1a | N/A | Yang et al., 2015 |
| MO2-vcam1a | N/A | Yang et al., 2015 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin C1-set | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Intercellular adhesion molecule, N-terminal | Intercellular adhesion molecule/vascular cell adhesion molecule |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F6NRL9 | InterPro | 440 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
vcam1a-201
(1)
|
Ensembl | 1,703 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-60B12 | ZFIN Curated Data |
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| Type | Accession # | Genome Assembly | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_073923078 (1) | GRCz12tu | 2686 nt | |
| Genomic | GenBank:AL953893 (1) | 216749 nt | ||
| Polypeptide | UniProtKB:F6NRL9 (1) | 440 aa |
- Li, X., Yang, S., Zhang, X., Zhang, Y., Zhang, Y., Li, H. (2024) Bioinformatic Analysis of Roquin Family Reveals Their Potential Role in Immune System. International Journal of Molecular Sciences. 25(11):
- Ranjan, G., Sehgal, P., Scaria, V., Sivasubbu, S. (2024) SCAR-6 elncRNA locus epigenetically regulates PROZ and modulates coagulation and vascular function. EMBO reports. 25(11):4950-4978
- Yang, Y., Enis, D., Zheng, H., Chia, S., Yang, J., Chen, M., Dhillon, V., Papayannapoulou, T., Kahn, M.L. (2015) Cell Adhesion Mediated by VCAM-ITGa9 Interactions Enables Lymphatic Development. Arterioscler. Thromb. Vasc. Biol.. 35(5):1179-89
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