ZFIN is now using GRCz12tu for Genomic Data
Gene
dennd1b
- ID
- ZDB-GENE-060503-16
- Name
- DENN/MADD domain containing 1B
- Symbol
- dennd1b Nomenclature History
- Previous Names
-
- si:ch211-195i21.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable phosphatidylinositol phosphate binding activity. Predicted to be involved in endocytic recycling and endocytosis. Predicted to be active in cytosol. Is expressed in forebrain and hypothalamus. Human ortholog(s) of this gene implicated in allergic asthma; asthma; childhood-onset asthma; and intrinsic asthma. Orthologous to human DENND1B (DENN domain containing 1B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Yelin-Bekerman et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | cDENN domain | dDENN domain | DENN domain-containing protein 1A/1B/1C | DENN domain, C-terminal lobe | Tripartite DENN domain | uDENN domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PDK2 | InterPro | 336 | ||||||
| UniProtKB:A0A8M3B5N2 | InterPro | 754 | ||||||
| UniProtKB:A0AC58IIA5 | InterPro | 774 | ||||||
| UniProtKB:A0AC58IIB5 | InterPro | 734 | ||||||
| UniProtKB:A0AC58IID4 | InterPro | 754 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dennd1b-201
(1)
|
Ensembl | 2,317 nt | ||
| mRNA |
dennd1b-202
(1)
|
Ensembl | 879 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers