Gene
pold1
- ID
- ZDB-GENE-060429-1
- Name
- polymerase (DNA directed), delta 1, catalytic subunit
- Symbol
- pold1 Nomenclature History
- Previous Names
-
- fla
- flat head
- im:7139126
- zgc:152688
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have 3'-5'-exodeoxyribonuclease activity and DNA-directed DNA polymerase activity. Involved in DNA replication. Predicted to localize to delta DNA polymerase complex. Is expressed in several structures, including brain; immature eye; neural crest; proliferative region; and retina. Orthologous to human POLD1 (DNA polymerase delta 1, catalytic subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7139126 (7 images)
- IMAGE:7160082 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017964 | DNA-directed DNA polymerase, family B, conserved site |
| Domain | IPR006133 | DNA-directed DNA polymerase, family B, exonuclease domain |
| Domain | IPR006134 | DNA-directed DNA polymerase, family B, multifunctional domain |
| Domain | IPR025687 | C4-type zinc-finger of DNA polymerase delta |
| Family | IPR006172 | DNA-directed DNA polymerase, family B |
| Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
| Homologous_superfamily | IPR023211 | DNA polymerase, palm domain superfamily |
| Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
| Homologous_superfamily | IPR042087 | DNA polymerase family B, thumb domain |
| Homologous_superfamily | IPR043502 | DNA/RNA polymerase superfamily |
Domain Details Per Protein
| Protein | Length | C4-type zinc-finger of DNA polymerase delta | DNA-directed DNA polymerase, family B | DNA-directed DNA polymerase, family B, conserved site | DNA-directed DNA polymerase, family B, exonuclease domain | DNA-directed DNA polymerase, family B, multifunctional domain | DNA polymerase family B, thumb domain | DNA polymerase, palm domain superfamily | DNA/RNA polymerase superfamily | Ribonuclease H-like superfamily | Ribonuclease H superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q2KNE0
|
1105 |
Interactions and Pathways
No data available
Plasmids
No data available