tnfaip6

ID

ZDB-GENE-060421-2654

Name

tumor necrosis factor, alpha-induced protein 6

Symbol

tnfaip6 Nomenclature History

Previous Names

si:dkey-89p3.1
zgc:136830

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable hyaluronic acid binding activity. Predicted to be involved in negative regulation of inflammatory response. Predicted to act upstream of or within cell adhesion. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in corneal neovascularization. Orthologous to human TNFAIP6 (TNF alpha induced protein 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Tsata et al., 2020

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tnfaip6 Human Ortholog

No data available

Associated With tnfaip6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000538	Link domain
Domain	IPR000859	CUB domain
Family	IPR052129	Spermadhesin-Link domain-containing protein
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Homologous_superfamily	IPR035914	Spermadhesin, CUB domain superfamily