ZFIN is now using GRCz12tu for Genomic Data
Gene
rtn2b
- ID
- ZDB-GENE-060331-95
- Name
- reticulon 2b
- Symbol
- rtn2b Nomenclature History
- Previous Names
-
- rtn8 (1)
- zgc:136618
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be located in endoplasmic reticulum membrane. Is expressed in skeletal muscle. Human ortholog(s) of this gene implicated in autosomal recessive distal hereditary motor neuronopathy and hereditary spastic paraplegia 12. Orthologous to human RTN2 (reticulon 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Housley et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 12 | Alliance | Spastic paraplegia 12, autosomal dominant | 604805 |
| Neuronopathy, distal hereditary motor, autosomal recessive 11, with spasticity | 620854 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Reticulon | Reticulon 1-4 |
|---|---|---|---|---|
| UniProtKB:Q4G5T7 | InterPro | 208 | ||
| UniProtKB:A0A8M9PQI6 | InterPro | 204 | ||
| UniProtKB:A0A8M2B839 | InterPro | 161 | ||
| UniProtKB:A0AC58I9I6 | InterPro | 204 | ||
| UniProtKB:A0AC58I9J1 | InterPro | 161 | ||
| UniProtKB:A0AC58I9K7 | InterPro | 161 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers