Gene

rac1l

ID
ZDB-GENE-060315-6
Name
Rac family small GTPase 1, like
Symbol
rac1l Nomenclature History
Previous Names
  • Rac1b (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including Ras protein signal transduction; engulfment of apoptotic cell; and motor neuron axon guidance. Predicted to localize to several cellular components, including cell cortex; cytoplasmic vesicle; and cytoskeleton. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 48; colon adenocarcinoma; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Hung et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rac1l Human Ortholog
No data available
Associated With rac1l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005225 Small GTP-binding protein domain
Family IPR001806 Small GTPase
Family IPR003578 Small GTPase Rho
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase Small GTPase Small GTPase Rho Small GTP-binding protein domain
UniProtKB:A0A8M1Q142 192
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA rac1l-201 (1) Havana 2150 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations