ZFIN is now using GRCz12tu for Genomic Data
Gene
slc7a7
- ID
- ZDB-GENE-051127-5
- Name
- solute carrier family 7 member 7
- Symbol
- slc7a7 Nomenclature History
- Previous Names
-
- unm t30713
- unm_t30713
- zgc:123300
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable L-amino acid transmembrane transporter activity and basic amino acid transmembrane transporter activity. Acts upstream of or within microglia development. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain; myeloid cell; and pancreatic D cell. Used to study lysinuric protein intolerance. Human ortholog(s) of this gene implicated in lysinuric protein intolerance. Orthologous to human SLC7A7 (solute carrier family 7 member 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| lysinuric protein intolerance | Alliance | Lysinuric protein intolerance | 222700 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| lysinuric protein intolerance | slc7a7t30713/t30713 | standard conditions | Rossi et al., 2015 |
| lysinuric protein intolerance | WT + MO1-slc7a7 | standard conditions | Rossi et al., 2015 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Amino acid/polyamine transporter I | Cellular Amino Acid Transporter |
|---|---|---|---|---|
| UniProtKB:Q2YDQ4 | InterPro | 501 | ||
| UniProtKB:A0A8M1N819 | InterPro | 501 | ||
| UniProtKB:A0AC58G0C8 | InterPro | 501 | ||
| UniProtKB:A0AC58G0K9 | InterPro | 501 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc7a7-201
(1)
|
Ensembl | 2,395 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers