Gene

sla1a

ID
ZDB-GENE-050904-3
Name
Src like adaptor 1a
Symbol
sla1a Nomenclature History
Previous Names
  • sla1
  • zgc:113360 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in several processes, including peptidyl-tyrosine autophosphorylation; regulation of cell population proliferation; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to extrinsic component of cytoplasmic side of plasma membrane. Is expressed in macrophage. Orthologous to human SLA (Src like adaptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sla1a Human Ortholog
No data available
Associated With sla1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR001452 SH3 domain
Domain IPR035052 SLAP, SH2 domain
Domain IPR035596 Src-like-adapter, SH3 domain
Family IPR043539 Grb2-like
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length Grb2-like SH2 domain SH2 domain superfamily SH3 domain SH3-like domain superfamily SLAP, SH2 domain Src-like-adapter, SH3 domain
UniProtKB:Q3ZB94 271
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations