ZFIN is now using GRCz12tu for Genomic Data
Gene
mtmr1a
- ID
- ZDB-GENE-050522-518
- Name
- myotubularin related protein 1a
- Symbol
- mtmr1a Nomenclature History
- Previous Names
-
- mtmr1 (1)
- zgc:113282
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity and phosphatidylinositol-3-phosphate phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Predicted to be active in cytoplasm and membrane. Is expressed in central nervous system; retina; and trigeminal placode. Orthologous to human MTMR1 (myotubularin related protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7159559 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
| Domain | IPR004182 | GRAM domain |
| Domain | IPR010569 | Myotubularin-like, phosphatase domain |
| Domain | IPR037857 | MTMR1, PH-GRAM |
| Family | IPR030564 | Myotubularin |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | GRAM domain | MTMR1, PH-GRAM | Myotubularin | Myotubularin-like, phosphatase domain | PH-like domain superfamily | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2BJN3 | InterPro | 691 | ||||||||
| UniProtKB:Q501S9 | InterPro | 683 | ||||||||
| UniProtKB:A0A8M3B3Y3 | InterPro | 699 | ||||||||
| UniProtKB:A0A8M2BJP1 | InterPro | 669 | ||||||||
| UniProtKB:A0A8M3B116 | InterPro | 677 | ||||||||
| UniProtKB:A0AB32TU15 | InterPro | 677 | ||||||||
| UniProtKB:A0AB32TUZ7 | InterPro | 669 | ||||||||
| UniProtKB:A0AC58FYQ1 | InterPro | 691 | ||||||||
| UniProtKB:A0AC58FYQ3 | InterPro | 699 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mtmr1a-201
(1)
|
Ensembl | 2,294 nt | ||
| mRNA |
mtmr1a-202
(1)
|
Ensembl | 3,985 nt | ||
| ncRNA |
mtmr1a-002
(1)
|
Ensembl | 460 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers