ZFIN is now using GRCz12tu for Genomic Data
Gene

fcho2

ID
ZDB-GENE-050522-228
Name
FCH and mu domain containing endocytic adaptor 2
Symbol
fcho2 Nomenclature History
Previous Names
  • cb304 (1)
  • sb:cb304
  • si:ch211-195c22.1
  • wu:fa01a02
  • zgc:112167
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity and phosphatidylserine binding activity. Acts upstream of or within chordate embryonic development and convergent extension involved in axis elongation. Predicted to be located in membrane. Predicted to be active in clathrin-coated pit; clathrin-coated vesicle; and plasma membrane. Is expressed in anterior axial hypoblast; hatching gland; immature eye; polster; and yolk syncytial layer. Orthologous to human FCHO2 (FCH and mu domain containing endocytic adaptor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Umasankar et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fcho2 Human Ortholog
No data available
Associated With fcho2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001060 FCH domain
Domain IPR018808 Muniscin, C-terminal
Domain IPR028565 Mu homology domain
Domain IPR030122 F-BAR domain only protein 2, F-BAR domain
Domain IPR031160 F-BAR domain
Domain IPR054713 GMIP/FCHO2-like, FCH domain
Homologous_superfamily IPR027267 AH/BAR domain superfamily
Homologous_superfamily IPR036168 AP-2 complex subunit mu, C-terminal superfamily
Domain Details Per Protein
Protein Additional Resources Length AH/BAR domain superfamily AP-2 complex subunit mu, C-terminal superfamily F-BAR domain F-BAR domain only protein 2, F-BAR domain FCH domain GMIP/FCHO2-like, FCH domain Mu homology domain Muniscin, C-terminal
UniProtKB:A0A8M9QDY0 InterPro 1059
UniProtKB:A0A8M9Q8L9 InterPro 1044
UniProtKB:A0A8M9Q3B6 InterPro 862
UniProtKB:A0A8M3ASB7 InterPro 863
UniProtKB:A0A8M2BJ82 InterPro 1018
UniProtKB:A0A8M3B2H5 InterPro 1034
UniProtKB:A0A8M9PXK6 InterPro 1039
UniProtKB:A0A8M3AZM0 InterPro 1033
UniProtKB:A0A8M9PK46 InterPro 1043
UniProtKB:Q502I9 InterPro 848
UniProtKB:A0A8M3B9M8 InterPro 843
UniProtKB:A0AB32TN48 InterPro 1034
UniProtKB:A0AB32TN63 InterPro 1033
UniProtKB:A0AB32TPA2 InterPro 828
UniProtKB:A0AB32TPG8 InterPro 843
UniProtKB:A0AB32TRI4 InterPro 863
UniProtKB:A0AB32TRU7 InterPro 1060
UniProtKB:A0AB32TTE6 InterPro 1059
UniProtKB:A0AB32TTL7 InterPro 862
UniProtKB:A0AB32TUE4 InterPro 1044
UniProtKB:A0AB32TV62 InterPro 1040
UniProtKB:A0AB32TVB7 InterPro 1059
UniProtKB:A0AB32TWN0 InterPro 1045
UniProtKB:A0AC58JJ52 InterPro 1043
UniProtKB:A0AC58JJ53 InterPro 1045
UniProtKB:A0AC58JJ55 InterPro 1044
UniProtKB:A0AC58JJ56 InterPro 1034
UniProtKB:A0AC58JJ57 InterPro 1013
UniProtKB:A0AC58JJ58 InterPro 1031
UniProtKB:A0AC58JJ59 InterPro 1030
UniProtKB:A0AC58JJ60 InterPro 1025
UniProtKB:A0AC58JJ61 InterPro 1092
UniProtKB:A0AC58JJ62 InterPro 1024
UniProtKB:A0AC58JJ63 InterPro 1018
UniProtKB:A0AC58JJ64 InterPro 1019
UniProtKB:A0AC58JJ65 InterPro 1017
UniProtKB:A0AC58JJ66 InterPro 1044
UniProtKB:A0AC58JJ67 InterPro 998
UniProtKB:A0AC58JJ68 InterPro 1033
UniProtKB:A0AC58JJ69 InterPro 862
UniProtKB:A0AC58JJ70 InterPro 863
UniProtKB:A0AC58JJ71 InterPro 998
UniProtKB:A0AC58JJ72 InterPro 842
UniProtKB:A0AC58JJ74 InterPro 843
UniProtKB:A0AC58JJ75 InterPro 827
UniProtKB:A0AC58JJ76 InterPro 999
UniProtKB:A0AC58JJ77 InterPro 847
UniProtKB:A0AC58JJ78 InterPro 860
UniProtKB:A0AC58JJ80 InterPro 997
UniProtKB:A0AC58JJ82 InterPro 828
UniProtKB:A0AC58JJ87 InterPro 859
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA fcho2-201 (1) Ensembl 2,547 nt
mRNA fcho2-202 (1) Ensembl 4,099 nt
mRNA fcho2-203 (1) Ensembl 3,291 nt
mRNA fcho2-204 (1) Ensembl 259 nt
mRNA fcho2-205 (1) Ensembl 3,379 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations