ZFIN is now using GRCz12tu for Genomic Data
Gene
abcg2d
- ID
- ZDB-GENE-050517-38
- Name
- ATP binding cassette subfamily G member 2 (JR blood group)
- Symbol
- abcg2d Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ATPase-coupled transmembrane transporter activity; efflux transmembrane transporter activity; and riboflavin transmembrane transporter activity. Predicted to be involved in sulfite export across plasma membrane and xenobiotic transport across blood-brain barrier. Predicted to be located in membrane. Predicted to be active in apical plasma membrane. Human ortholog(s) of this gene implicated in gout; hematologic cancer (multiple); renal cell carcinoma; and toxic encephalopathy. Orthologous to human ABCG2 (ATP binding cassette subfamily G member 2 (JR blood group)).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kobayashi et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003439 | ABC transporter-like, ATP-binding domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR013525 | ABC-2 type transporter, transmembrane domain |
| Domain | IPR043926 | ABC transporter family G domain |
| Family | IPR050352 | ATP-binding cassette subfamily G transporters |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | AAA+ ATPase domain | ABC-2 type transporter, transmembrane domain | ABC transporter family G domain | ABC transporter-like, ATP-binding domain | ATP-binding cassette subfamily G transporters | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q2Q444 | InterPro | 613 | ||||||
| UniProtKB:A0A8M3B3I6 | InterPro | 658 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
abcg2d-201
(1)
|
Ensembl | 1,842 nt | ||
| mRNA |
abcg2d-202
(1)
|
Ensembl | 2,112 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers