Gene

abcg2c

ID

ZDB-GENE-050517-37

Name

ATP-binding cassette, sub-family G (WHITE), member 2c

Symbol

abcg2c Nomenclature History

Previous Names

im:6903440

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in gout; hematologic cancer (multiple); renal cell carcinoma; and toxic encephalopathy. Is expressed in gill; hematopoietic system; and pleuroperitoneal region. Orthologous to human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:6903440 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcg2c Human Ortholog

No data available

Associated With abcg2c Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR013525	ABC-2 type transporter, transmembrane domain
Domain	IPR043926	ABC transporter family G domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	AAA+ ATPase domain	ABC-2 type transporter, transmembrane domain	ABC transporter family G domain	ABC transporter-like, ATP-binding domain	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M2B3F2 InterPro	640
UniProtKB:B8JI18 InterPro	634
UniProtKB:Q08CU5 InterPro	634

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	abcg2c-201 (1) Ensembl	Havana	2145 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	abcg2c-202 (1) Ensembl	Havana	914 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	abcg2c-203 (1) Ensembl	Havana	555 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations