Gene

afdna

ID

ZDB-GENE-050419-52

Name

afadin, adherens junction formation factor a

Symbol

afdna Nomenclature History

Previous Names

mllt4
mllt4a (1)
si:ch211-278j12.1

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have cell adhesion molecule binding activity. Predicted to be involved in regulation of protein localization. Predicted to localize to adherens junction. Orthologous to human AFDN (afadin, adherens junction formation factor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With afdna Human Ortholog

No data available

Associated With afdna Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000159	Ras-associating domain
Domain	IPR000253	Forkhead-associated (FHA) domain
Domain	IPR001478	PDZ domain
Domain	IPR002710	Dilute domain
Domain	IPR037977	Afadin, cargo binding domain
Homologous_superfamily	IPR008984	SMAD/FHA domain superfamily
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	Afadin, cargo binding domain	Dilute domain	Forkhead-associated (FHA) domain	PDZ domain	PDZ superfamily	Ras-associating domain	SMAD/FHA domain superfamily	Ubiquitin-like domain superfamily
UniProtKB:A0A8M9PHZ3 InterPro	1853
UniProtKB:A0A8M9P318 InterPro	1930
UniProtKB:A0A8M9PTH4 InterPro	1923
UniProtKB:A0A8M9PQ24 InterPro	1931
UniProtKB:A0A8M9P321 InterPro	1917
UniProtKB:A0A8M9PQ29 InterPro	1919
UniProtKB:A0A8M9PQ33 InterPro	1781
UniProtKB:A0A8M9PCC7 InterPro	1846
UniProtKB:A0A8M9PQ38 InterPro	1833
UniProtKB:A0A8M9PTF9 InterPro	1924
UniProtKB:A0A8M9PCB8 InterPro	1930
UniProtKB:A0A8M9PHZ9 InterPro	1746
UniProtKB:A0A8M9PTG9 InterPro	1681
UniProtKB:A0A8M9PCC2 InterPro	1854
UniProtKB:A0A8M9P326 InterPro	1918
UniProtKB:A0A8M9PHZ0 InterPro	1930
UniProtKB:A0A8M9PTG4 InterPro	1841
UniProtKB:A0A8M9P325 InterPro	1780
UniProtKB:A0A8M9PCC4 InterPro	1768

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	afdna-202 (1) Ensembl	Havana	8628 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations