ZFIN is now using GRCz12tu for Genomic Data
Gene
afdna
- ID
- ZDB-GENE-050419-52
- Name
- afadin, adherens junction formation factor a
- Symbol
- afdna Nomenclature History
- Previous Names
-
- mllt4
- mllt4a (1)
- si:ch211-278j12.1
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in adherens junction maintenance and cell-cell adhesion mediated by cadherin. Predicted to act upstream of or within cell adhesion and signal transduction. Predicted to be located in cell-cell junction and cytoplasm. Predicted to be active in adherens junction and plasma membrane. Orthologous to human AFDN (afadin, adherens junction formation factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000159 | Ras-associating domain |
| Domain | IPR000253 | Forkhead-associated (FHA) domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR002710 | Dilute domain |
| Domain | IPR037977 | Afadin, cargo binding domain |
| Family | IPR028842 | Afadin |
| Homologous_superfamily | IPR008984 | SMAD/FHA domain superfamily |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers