Gene
atg16l1
- ID
- ZDB-GENE-050417-401
- Name
- ATG16 autophagy related 16-like 1 (S. cerevisiae)
- Symbol
- atg16l1 Nomenclature History
- Previous Names
-
- fb57e05
- wu:fb57e05
- zgc:110147
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable identical protein binding activity. Predicted to be involved in autophagosome assembly and microautophagy. Predicted to be located in autophagosome membrane; cytosol; and phagophore assembly site membrane. Predicted to be part of Atg12-Atg5-Atg16 complex. Is expressed in intestine. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Orthologous to human ATG16L1 (autophagy related 16 like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110147 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| inflammatory bowel disease 10 | Alliance | {Inflammatory bowel disease (Crohn disease) 10} | 611081 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR013923 | Autophagy-related protein 16 domain |
| Family | IPR045160 | Autophagy-related protein 16 |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Autophagy-related protein 16 | Autophagy-related protein 16 domain | G-protein beta WD-40 repeat | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q568R2 | InterPro | 330 | |||||||
| UniProtKB:A0A8M1N5D3 | InterPro | 606 | |||||||
| UniProtKB:A0AB32T1C2 | InterPro | 621 | |||||||
| UniProtKB:A0AB32T1D2 | InterPro | 620 | |||||||
| UniProtKB:A0AB32T429 | InterPro | 605 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
atg16l1-201
(1)
|
Ensembl | 1,866 nt | ||
| mRNA |
atg16l1-202
(1)
|
Ensembl | 4,727 nt | ||
| mRNA |
atg16l1-203
(1)
|
Ensembl | 699 nt | ||
| mRNA |
atg16l1-204
(1)
|
Ensembl | 990 nt |
Interactions and Pathways
No data available
Plasmids
No data available