ZFIN is now using GRCz12tu for Genomic Data
Gene
iscub
- ID
- ZDB-GENE-050417-332
- Name
- iron-sulfur cluster assembly enzyme b
- Symbol
- iscub Nomenclature History
- Previous Names
-
- fj08f02
- wu:fj08f02
- zgc:110331
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable 2 iron, 2 sulfur cluster binding activity and ferrous iron binding activity. Predicted to be involved in intracellular iron ion homeostasis. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Orthologous to human ISCU (iron-sulfur cluster assembly enzyme).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Myopathy with lactic acidosis, hereditary | 255125 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Iron-sulfur cluster assembly scaffold protein IscU | NIF system FeS cluster assembly, NifU, N-terminal |
|---|---|---|---|---|
| UniProtKB:Q568F2 | InterPro | 164 | ||
| UniProtKB:F1QM53 | InterPro | 164 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers