ZFIN is now using GRCz12tu for Genomic Data
Gene
f3b
- ID
- ZDB-GENE-050417-234
- Name
- coagulation factor III, tissue factor b
- Symbol
- f3b Nomenclature History
- Previous Names
-
- TFb (1)
- zgc:112151
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cytokine receptor activity. Acts upstream of or within vasculature development. Predicted to be located in cell surface; extracellular region; and membrane. Predicted to be active in plasma membrane. Is expressed in hindbrain and otic vesicle. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; COVID-19; disseminated intravascular coagulation; and von Willebrand's disease. Orthologous to human F3 (coagulation factor III, tissue factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Zhou et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Interferon/interleukin receptor domain | Tissue factor |
|---|---|---|---|---|---|---|---|
| UniProtKB:B0UY88 | InterPro | 288 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers