Gene

agr2

ID
ZDB-GENE-050417-214
Name
anterior gradient 2
Symbol
agr2 Nomenclature History
Previous Names
  • sb:eu228
  • wu:fj29g05
  • zgc:112187
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have protein homodimerization activity. Involved in intestinal epithelial cell differentiation. Predicted to localize to endoplasmic reticulum and extracellular region. Human ortholog(s) of this gene implicated in in situ carcinoma. Is expressed in several structures, including digestive system; hatching gland; integument; olfactory system; and vestibuloauditory system. Orthologous to several human genes including AGR2 (anterior gradient 2, protein disulphide isomerase family member).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
44 figures from 16 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Chen et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With agr2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Respiratory infections, recurrent, and failure to thrive with or without diarrhea 620233
Associated With agr2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length Thioredoxin-like superfamily
UniProtKB:Q5RZ65 171
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations