Gene
nalcn
- ID
- ZDB-GENE-050410-12
- Name
- sodium leak channel, non-selective
- Symbol
- nalcn Nomenclature History
- Previous Names
-
- zgc:113349
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have cation channel activity. Predicted to be involved in ion transport and transmembrane transport. Predicted to localize to integral component of membrane. Is expressed in central nervous system. Orthologous to human NALCN (sodium leak channel, non-selective).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7147273 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital limbs-face contractures-hypotonia-developmental delay syndrome | Alliance | Congenital contractures of the limbs and face, hypotonia, and developmental delay | 616266 |
| Hypotonia, infantile, with psychomotor retardation and characteristic facies 1 | 615419 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ion transport domain | Sodium leak channel NALCN | Voltage-dependent channel domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A0A8M3B5P5
|
1741 | |||
|
UniProtKB:A0A8M2BF56
|
1743 | |||
|
UniProtKB:F1QCP2
|
1742 |
Interactions and Pathways
No data available
Plasmids
No data available