ZFIN is now using GRCz12tu for Genomic Data
Gene
eya4
- ID
- ZDB-GENE-050327-93
- Name
- EYA transcriptional coactivator and phosphatase 4
- Symbol
- eya4 Nomenclature History
- Previous Names
-
- im:7221408
- zgc:113079
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within embryonic organ development; posterior lateral line neuromast hair cell differentiation; and startle response. Predicted to be active in nucleus. Is expressed in several structures, including otic vesicle; pericardial region; pharyngeal arch; swim bladder; and vestibuloauditory system. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 10; congestive heart failure; dilated cardiomyopathy; dilated cardiomyopathy 1J; and sensorineural hearing loss. Orthologous to human EYA4 (EYA transcriptional coactivator and phosphatase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Wang et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 10 | Alliance | Deafness, autosomal dominant 10 | 601316 |
| dilated cardiomyopathy 1J | Alliance | ?Cardiomyopathy, dilated, 1J | 605362 |
Domain, Family, and Site Summary
Domain Details Per Protein
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers