ZFIN is now using GRCz12tu for Genomic Data
Gene
cacna2d2a
- ID
- ZDB-GENE-050320-71
- Name
- calcium channel, voltage-dependent, alpha 2/delta subunit 2a
- Symbol
- cacna2d2a Nomenclature History
- Previous Names
-
- cacna2d2
- cacna2d2b
- si:dkey-18h3.3
- zgc:113325
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium channel activity. Predicted to act upstream of or within calcium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of monoatomic ion channel complex. Orthologous to human CACNA2D2 (calcium voltage-gated channel auxiliary subunit alpha2delta 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cerebellar atrophy with seizures and variable developmental delay | 618501 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002035 | von Willebrand factor, type A |
| Domain | IPR013608 | VWA N-terminal |
| Domain | IPR013680 | Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region |
| Family | IPR051173 | Voltage-dependent calcium channel subunit alpha-2/delta |
| Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region | Voltage-dependent calcium channel subunit alpha-2/delta | von Willebrand factor A-like domain superfamily | von Willebrand factor, type A | VWA N-terminal |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3ATR3 | InterPro | 1103 | |||||
| UniProtKB:A0A1D5NSP7 | InterPro | 451 | |||||
| UniProtKB:A0A8M3B0S8 | InterPro | 1109 | |||||
| UniProtKB:A0A8M3BAM9 | InterPro | 631 | |||||
| UniProtKB:A0AB40E7N5 | InterPro | 1109 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cacna2d2a-201
(1)
|
Ensembl | 1,668 nt | ||
| mRNA |
cacna2d2a-202
(1)
|
Ensembl | 1,739 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers