ZFIN is now using GRCz12tu for Genomic Data
Gene
arsa
- ID
- ZDB-GENE-050320-118
- Name
- arylsulfatase A
- Symbol
- arsa Nomenclature History
- Previous Names
-
- zgc:101575
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable arylsulfatase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in endoplasmic reticulum and lysosome. Human ortholog(s) of this gene implicated in metachromatic leukodystrophy. Orthologous to human ARSA (arylsulfatase A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101575 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Berg et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| metachromatic leukodystrophy | Alliance | Metachromatic leukodystrophy | 250100 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Alkaline-phosphatase-like, core domain superfamily | Sulfatase, conserved site | Sulfatase enzyme | Sulfatase, N-terminal |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1N4V1 | InterPro | 503 | ||||
| UniProtKB:Q5BL32 | InterPro | 499 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers