Gene

gstm.3

ID
ZDB-GENE-050309-24
Name
glutathione S-transferase mu tandem duplicate 3
Symbol
gstm.3 Nomenclature History
Previous Names
  • gstm3 (1)
  • im:6897516
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Enables glutathione transferase activity. Involved in glutathione metabolic process. Is expressed in brain; gill; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to several human genes including GSTM1 (glutathione S-transferase mu 1); GSTM2 (glutathione S-transferase mu 2); and GSTM3 (glutathione S-transferase mu 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gstm.3 Human Ortholog
No data available
Associated With gstm.3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004045 Glutathione S-transferase, N-terminal
Domain IPR004046 Glutathione S-transferase, C-terminal
Domain IPR010987 Glutathione S-transferase, C-terminal-like
Family IPR003081 Glutathione S-transferase, Mu class
Family IPR040079 Glutathione Transferase family
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Homologous_superfamily IPR036282 Glutathione S-transferase, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Glutathione S-transferase, C-terminal Glutathione S-transferase, C-terminal domain superfamily Glutathione S-transferase, C-terminal-like Glutathione S-transferase, Mu class Glutathione S-transferase, N-terminal Glutathione Transferase family Thioredoxin-like superfamily
UniProtKB:B8JIS5 219
UniProtKB:B8JIS6 122
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations