Gene

sfxn4

ID
ZDB-GENE-050309-187
Name
sideroflexin 4
Symbol
sfxn4 Nomenclature History
Previous Names
  • im:7151335 (1)
  • si:ch211-117n7.3
  • zgc:153199
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have transmembrane transporter activity. Involved in cellular respiration and erythrocyte differentiation. Localizes to mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 18. Orthologous to human SFXN4 (sideroflexin 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Hildick-Smith et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sfxn4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined oxidative phosphorylation deficiency 18 Alliance Combined oxidative phosphorylation deficiency 18 615578
Associated With sfxn4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004686 Tricarboxylate/iron carrier
Family IPR028825 Sideroflexin-4
Domain Details Per Protein
Protein Length Sideroflexin-4 Tricarboxylate/iron carrier
UniProtKB:A8E7G5 316
UniProtKB:A0A2R8QPY5 316
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations