bmp6

ID

ZDB-GENE-050306-42

Name

bone morphogenetic protein 6

Symbol

bmp6 Nomenclature History

Previous Names

zgc:113595

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable cytokine activity. Acts upstream of or within bone morphogenesis. Predicted to be active in extracellular region. Is expressed in several structures, including choroidal fissure; ectoderm; fin; intermuscular bone; and ventral mesoderm. Orthologous to human BMP6 (bone morphogenetic protein 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

18 figures from 11 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7139175 (27 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With bmp6 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		{Iron overload, susceptibility to}	620121

Associated With bmp6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017948	Transforming growth factor beta, conserved site
Domain	IPR001111	TGF-beta, propeptide
Domain	IPR001839	Transforming growth factor-beta, C-terminal
Family	IPR015615	Transforming growth factor-beta-like
Homologous_superfamily	IPR029034	Cystine-knot cytokine

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PFZ4	InterPro	406
UniProtKB:Q5CZV5	InterPro	417
UniProtKB:A0AC58IQD3	InterPro	406
UniProtKB:A0AC58IQD4	InterPro	296
UniProtKB:A0AC58IQE0	InterPro	285