Gene

scube2

ID
ZDB-GENE-050302-80
Name
signal peptide, CUB domain, EGF-like 2
Symbol
scube2 Nomenclature History
Previous Names
  • U shaped somites
  • u-shaped somites (1)
  • wu:fc27f08
  • you
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Involved in several processes, including muscle cell fate specification; muscle fiber development; and negative regulation of BMP signaling pathway. Localizes to cell surface; extracellular region; and secretory granule. Is expressed in several structures, including central nervous system; midbrain hindbrain boundary neural rod; midbrain neural rod; neural keel; and trunk. Orthologous to human SCUBE2 (signal peptide, CUB domain and EGF like domain containing 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With scube2 Human Ortholog
No data available
Associated With scube2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000742 EGF-like domain
Domain IPR000859 CUB domain
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like
Domain IPR024731 EGF domain
Domain IPR026823 Complement Clr-like EGF domain
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR035914 Spermadhesin, CUB domain superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length Complement Clr-like EGF domain CUB domain EGF domain EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site Growth factor receptor cysteine-rich domain superfamily Spermadhesin, CUB domain superfamily Tyrosine-protein kinase ephrin type A/B receptor-like
UniProtKB:F1Q6K4 1010
UniProtKB:A0A0B5JWE1 1010
UniProtKB:Q5G872 1010
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations