Gene

gna12a

ID
ZDB-GENE-050221-1
Name
guanine nucleotide binding protein (G protein) alpha 12a
Symbol
gna12a Nomenclature History
Previous Names
  • gna12
  • gna12l (1)
  • Galpha 12 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have D5 dopamine receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in several processes, including gastrulation; glial cell development; and negative regulation of cell-cell adhesion mediated by cadherin. Predicted to localize to brush border membrane and heterotrimeric G-protein complex. Is expressed in brain; gill; head; and olfactory epithelium. Orthologous to human GNA12 (G protein subunit alpha 12).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gna12a Human Ortholog
No data available
Associated With gna12a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000469 G-protein alpha subunit, group 12/13
Family IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
Homologous_superfamily IPR011025 G protein alpha subunit, helical insertion
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length G-protein alpha subunit, group 12/13 G protein alpha subunit, helical insertion Guanine nucleotide binding protein (G-protein), alpha subunit P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q5YKG4 385
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations