Gene
shc2
- ID
- ZDB-GENE-050208-666
- Name
- SHC (Src homology 2 domain containing) transforming protein 2
- Symbol
- shc2 Nomenclature History
- Previous Names
-
- si:dkey-94n12.3
- zgc:162768
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have receptor tyrosine kinase binding activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to plasma membrane. Orthologous to human SHC2 (SHC adaptor protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Yang et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000980 | SH2 domain |
| Domain | IPR006019 | Phosphotyrosine interaction domain, Shc-like |
| Domain | IPR006020 | PTB/PI domain |
| Domain | IPR035676 | SH2 adaptor protein C, SH2 domain |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
Domain Details Per Protein
| Protein | Length | PH-like domain superfamily | Phosphotyrosine interaction domain, Shc-like | PTB/PI domain | SH2 adaptor protein C, SH2 domain | SH2 domain | SH2 domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AUP6
|
492 | ||||||
|
UniProtKB:Q1LX18
|
501 | ||||||
|
UniProtKB:A0A8M6YXA6
|
679 | ||||||
|
UniProtKB:A0A8M6Z438
|
678 |
Interactions and Pathways
No data available
Plasmids
No data available