ZFIN is now using GRCz12tu for Genomic Data
Gene

lrp1ba

ID
ZDB-GENE-050208-608
Name
low density lipoprotein receptor-related protein 1Ba
Symbol
lrp1ba Nomenclature History
Previous Names
  • lrp1b
  • si:ch211-181p13.1
  • si:dkeyp-122a9.3
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung disease (multiple); and melanoma. Orthologous to human LRP1B (LDL receptor related protein 1B).
Genome Resources
Note
lrp1ba is represented by at least two gene models in Ensembl GRCz11.
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lrp1ba Human Ortholog
No data available
Associated With lrp1ba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Conserved_site IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
Domain IPR000742 EGF-like domain
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR026823 Complement Clr-like EGF domain
Domain IPR049883 NOTCH1, EGF-like calcium-binding domain
Domain IPR056588 LRP2, EGF-like domain
Family IPR051221 Low-density lipoprotein receptor-related
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR011042 Six-bladed beta-propeller, TolB-like
Homologous_superfamily IPR036055 LDL receptor-like superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Repeat IPR000033 LDLR class B repeat
Repeat IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
Domain Details Per Protein
Protein Additional Resources Length Complement Clr-like EGF domain EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site Growth factor receptor cysteine-rich domain superfamily LDLR class B repeat LDL receptor-like superfamily Low-density lipoprotein (LDL) receptor class A, conserved site Low-density lipoprotein (LDL) receptor class A repeat Low-density lipoprotein receptor-related LRP2, EGF-like domain NOTCH1, EGF-like calcium-binding domain Six-bladed beta-propeller, TolB-like
UniProtKB:A0AC58IH39 InterPro 2731
UniProtKB:A0A8M6YV36 InterPro 4616
UniProtKB:A0A8M9PEH3 InterPro 4654
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lrp1ba-201 (1)
Ensembl
Ensembl 8,684 nt
ZFIN BLAST
mRNA lrp1ba-203 (1)
Ensembl
Ensembl 4,890 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Citations
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