Gene

loxl2b

ID
ZDB-GENE-050208-29
Name
lysyl oxidase-like 2b
Symbol
loxl2b Nomenclature History
Previous Names
  • im:7136137
  • si:dkeyp-32b1.1
  • wu:fk12g04
  • zgc:158414
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity; copper ion binding activity; and protein-lysine 6-oxidase activity. Predicted to be involved in several processes, including collagen fibril organization; peptidyl-lysine oxidation; and positive regulation of cell differentiation. Predicted to localize to several cellular components, including basement membrane; chromatin; and endoplasmic reticulum. Is expressed in diencephalon; head mesenchyme; hindbrain; notochord; and pectoral fin. Orthologous to human LOXL2 (lysyl oxidase like 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
17 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Gansner et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With loxl2b Human Ortholog
No data available
Associated With loxl2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019828 Lysyl oxidase, conserved site
Domain IPR001190 SRCR domain
Domain IPR017448 SRCR-like domain
Family IPR001695 Lysyl oxidase
Homologous_superfamily IPR036772 SRCR-like domain superfamily
Domain Details Per Protein
Protein Length Lysyl oxidase Lysyl oxidase, conserved site SRCR domain SRCR-like domain SRCR-like domain superfamily
UniProtKB:A1L1V4 762
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA loxl2b-202 (1) Havana 3555 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations