Gene
gcm2
- ID
- ZDB-GENE-050127-1
- Name
- glial cells missing transcription factor 2
- Symbol
- gcm2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Is predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in gliogenesis and regulation of transcription by RNA polymerase II. Acts upstream of or within animal organ development; epidermal cell fate specification; and metal ion homeostasis. Is expressed in several structures, including ectoderm; head; macrophage; pharynx; and yolk. Human ortholog(s) of this gene implicated in familial isolated hypoparathyroidism and hyperparathyroidism. Orthologous to human GCM2 (glial cells missing transcription factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Chorion-specific transcription factor GCM | GCM domain superfamily | GCM, small domain | Transcription regulator GCM domain |
|---|---|---|---|---|---|
|
UniProtKB:Q68BU9
|
496 | ||||
|
UniProtKB:Q5TLZ9
|
478 | ||||
|
UniProtKB:Q2KT54
|
496 |
Interactions and Pathways
No data available
Plasmids
No data available