ZFIN is now using GRCz12tu for Genomic Data
Gene
ada2b
- ID
- ZDB-GENE-041210-77
- Name
- adenosine deaminase 2b
- Symbol
- ada2b Nomenclature History
- Previous Names
-
- ADA2-2 (1)
- cecr1b
- si:ch211-214j24.5
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable adenosine deaminase activity. Predicted to be involved in adenosine catabolic process and inosine biosynthetic process. Predicted to be active in extracellular region. Is expressed in several structures, including cardiovascular system; gill; liver; notochord; and pleuroperitoneal region. Used to study adenosine deaminase deficiency. Human ortholog(s) of this gene implicated in Sneddon syndrome. Orthologous to human ADA2 (adenosine deaminase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Sneddon syndrome | Alliance | Sneddon syndrome | 182410 |
| Vasculitis, autoinflammation, immunodeficiency, and hematologic defects syndrome | 615688 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Adenosine/adenine deaminase | Adenosine/AMP deaminase N-terminal | Adenosine deaminase domain | Adenosine deaminase-related growth factor | Metal-dependent hydrolase |
|---|---|---|---|---|---|---|---|
| UniProtKB:F6NKG5 | InterPro | 501 | |||||
| UniProtKB:A0AC58J9A6 | InterPro | 488 | |||||
| UniProtKB:A0ACD6B6N6 | InterPro | 501 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers