ZFIN is now using GRCz12tu for Genomic Data
Gene
lmod2b
- ID
- ZDB-GENE-041210-356
- Name
- leiomodin 2 (cardiac) b
- Symbol
- lmod2b Nomenclature History
- Previous Names
-
- si:dkey-3n7.4
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable tropomyosin binding activity. Predicted to be involved in actin filament organization; muscle contraction; and myofibril assembly. Predicted to act upstream of or within pointed-end actin filament capping. Predicted to be active in striated muscle thin filament. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2G. Orthologous to human LMOD2 (leiomodin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| dilated cardiomyopathy 2G | Alliance | Cardiomyopathy, dilated, 2G | 619897 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Leucine-rich repeat domain superfamily | Tropomodulin |
|---|---|---|---|---|
| UniProtKB:F1Q5L7 | InterPro | 596 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lmod2b-201
(1)
|
Ensembl | 1,791 nt | ||
| mRNA |
lmod2b-202
(1)
|
Ensembl | 1,812 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers