Gene
eif4eb
- ID
- ZDB-GENE-041121-14
- Name
- eukaryotic translation initiation factor 4eb
- Symbol
- eif4eb Nomenclature History
- Previous Names
-
- zgc:101581 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to act upstream of or within mRNA transport; regulation of translation; and translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in several structures, including hatching gland; head; optic tectum; polster; and solid lens vesicle. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human EIF4E (eukaryotic translation initiation factor 4E).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101581 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Autism, susceptibility to, 19} | 615091 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Eukaryotic translation initiation factor 4E (eIF-4E), conserved site | Translation Initiation factor eIF- 4e | Translation Initiation factor eIF- 4e-like |
|---|---|---|---|---|---|
| UniProtKB:Q5RKQ5 | InterPro | 216 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
eif4eb-201
(1)
|
Ensembl | 1,563 nt |
Interactions and Pathways
No data available
Plasmids
No data available