Gene
vtnb
- ID
- ZDB-GENE-041116-1
- Name
- vitronectin b
- Symbol
- vtnb Nomenclature History
- Previous Names
-
- vtn
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable extracellular matrix binding activity and integrin binding activity. Predicted to be involved in cell adhesion mediated by integrin and cell-matrix adhesion. Predicted to act upstream of or within immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix and extracellular space. Is expressed in hypothalamus; liver; liver primordium; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Churg-Strauss syndrome; granulomatosis with polyangiitis; and thrombosis. Orthologous to human VTN (vitronectin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907751 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000585 | Hemopexin-like domain |
Domain | IPR001212 | Somatomedin B domain |
Domain | IPR020436 | Somatomedin B domain, chordata |
Family | IPR051298 | Heme transport and cell adhesion protein |
Homologous_superfamily | IPR036024 | Somatomedin B-like domain superfamily |
Homologous_superfamily | IPR036375 | Hemopexin-like domain superfamily |
Repeat | IPR018487 | Hemopexin-like repeats |
Domain Details Per Protein
Protein | Additional Resources | Length | Heme transport and cell adhesion protein | Hemopexin-like domain | Hemopexin-like domain superfamily | Hemopexin-like repeats | Somatomedin B domain | Somatomedin B domain, chordata | Somatomedin B-like domain superfamily |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:F1Q5D8 | InterPro | 449 | |||||||
UniProtKB:A7E2Q3 | InterPro | 469 |
Interactions and Pathways
No data available
Plasmids
No data available