Gene
ftsj1
- ID
- ZDB-GENE-041114-83
- Name
- FtsJ RNA 2'-O-methyltransferase 1
- Symbol
- ftsj1 Nomenclature History
- Previous Names
-
- fb17g12
- wu:fb17g12
- zgc:101831
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have tRNA methyltransferase activity. Predicted to be involved in cytoplasmic translation and tRNA methylation. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101831 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| non-syndromic X-linked intellectual disability 9 | Alliance | Intellectual developmental disorder, X-linked 9 | 309549 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002877 | Ribosomal RNA methyltransferase, FtsJ domain |
| Family | IPR015507 | Ribosomal RNA large subunit methyltransferase E |
| Family | IPR028590 | tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase TRM7 |
| Homologous_superfamily | IPR029063 | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
Domain Details Per Protein
| Protein | Length | Ribosomal RNA large subunit methyltransferase E | Ribosomal RNA methyltransferase, FtsJ domain | S-adenosyl-L-methionine-dependent methyltransferase superfamily | tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase TRM7 |
|---|---|---|---|---|---|
|
UniProtKB:A8E5E3
|
323 | ||||
|
UniProtKB:F1QDU3
|
323 | ||||
|
UniProtKB:Q5U3P4
|
323 |
Interactions and Pathways
No data available
Plasmids
No data available