Gene

slc7a3a

ID
ZDB-GENE-041114-206
Name
solute carrier family 7 member 3a
Symbol
slc7a3a Nomenclature History
Previous Names
  • slc7a3 (1)
  • wu:fc11h09
  • zgc:92563
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable amino acid transmembrane transporter activity. Acts upstream of or within fatty acid metabolic process and triglyceride metabolic process. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in head. Used to study lipid storage disease and metabolic dysfunction-associated steatotic liver disease. Orthologous to human SLC7A3 (solute carrier family 7 member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Gu et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
ihb202TgTransgenic insertionExon 2UnknownDNA
sa23972Allele with one point mutationUnknownPremature StopENU
sa43672Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With slc7a3a Human Ortholog
No data available
Associated With slc7a3a Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR029485 Cationic amino acid transporter, C-terminal
Family IPR002293 Amino acid/polyamine transporter I
Family IPR004755 Cationic amino acid transport permease
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Domain Details Per Protein
Protein Additional Resources Length Amino acid/polyamine transporter I Cationic amino acid transporter, C-terminal Cationic amino acid transport permease
UniProtKB:F1R9X0 InterPro 644
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 21
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA slc7a3a-201 (1) Ensembl 4,457 nt
ncRNA slc7a3a-002 (1) Ensembl 536 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-173M3ZFIN Curated Data
Contained inBACDKEY-25L11ZFIN Curated Data
EncodesESTfc11h09
EncodesESTfb94c07ZFIN Curated Data
EncodescDNAMGC:92563ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanSLC7A3X
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseSlc7a3X
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 9 of 9
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