Gene

vps53

ID
ZDB-GENE-041114-199
Name
VPS53 subunit of GARP complex
Symbol
vps53 Nomenclature History
Previous Names
  • wu:fb77d11
  • zgc:103741 (1)
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to be located in Golgi apparatus and endosome membrane. Predicted to be part of GARP complex. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2E. Orthologous to human VPS53 (VPS53 subunit of GARP complex).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vps53 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pontocerebellar hypoplasia type 2E Alliance Pontocerebellar hypoplasia, type 2E 615851
Associated With vps53 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR039766 Vacuolar protein sorting-associated protein 53
Homologous_superfamily IPR038260 Vps53, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Vacuolar protein sorting-associated protein 53 Vps53, C-terminal domain superfamily
UniProtKB:E7FAG0 832
UniProtKB:A0A2R8QAM7 157
UniProtKB:Q5U3C9 158
UniProtKB:A0A2R8QRN0 158
UniProtKB:F6P6T6 831
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations