Gene

fbxl4

ID
ZDB-GENE-041114-187
Name
F-box and leucine-rich repeat protein 4
Symbol
fbxl4 Nomenclature History
Previous Names
  • zgc:92297
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 13. Orthologous to human FBXL4 (F-box and leucine rich repeat protein 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fbxl4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
mitochondrial DNA depletion syndrome 13 Alliance Mitochondrial DNA depletion syndrome 13 (encephalomyopathic type) 615471
Associated With fbxl4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001810 F-box domain
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Homologous_superfamily IPR036047 F-box-like domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR006553 Leucine-rich repeat, cysteine-containing subtype
Domain Details Per Protein
Protein Length F-box domain F-box-like domain superfamily Leucine-rich repeat Leucine-rich repeat, cysteine-containing subtype Leucine-rich repeat domain superfamily
UniProtKB:F1QWZ2 616
UniProtKB:Q5U388 607
UniProtKB:A0A0R4IWI4 607
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations