Gene
nansb
- ID
- ZDB-GENE-041114-125
- Name
- N-acetylneuraminic acid synthase b
- Symbol
- nansb Nomenclature History
- Previous Names
-
- zgc:101549 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have catalytic activity. Predicted to be involved in carbohydrate biosynthetic process. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Genevieve-type. Orthologous to human NANS (N-acetylneuraminate synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spondyloepimetaphyseal dysplasia, Genevieve-type | Alliance | Spondyloepimetaphyseal dysplasia, Genevieve type | 610442 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006190 | Antifreeze-like/N-acetylneuraminic acid synthase C-terminal |
| Domain | IPR013132 | N-acetylneuraminic acid synthase, N-terminal |
| Domain | IPR013974 | SAF domain |
| Homologous_superfamily | IPR013785 | Aldolase-type TIM barrel |
| Homologous_superfamily | IPR036732 | Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Aldolase-type TIM barrel | Antifreeze-like/N-acetylneuraminic acid synthase C-terminal | Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily | N-acetylneuraminic acid synthase, N-terminal | SAF domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q5U3W7
|
352 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available