ZFIN is now using GRCz12tu for Genomic Data
Gene
glmna
- ID
- ZDB-GENE-041114-120
- Name
- glomulin, FKBP associated protein a
- Symbol
- glmna Nomenclature History
- Previous Names
-
- glmnl (1)
- zgc:101567
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ubiquitin-protein transferase inhibitor activity. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in arteriovenous malformation; glomangioma; and glomus tumor. Orthologous to human GLMN (glomulin, FKBP associated protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7146372 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la014801Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| la023419Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa39778 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| glomangioma | Alliance | Glomuvenous malformations | 138000 |
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Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Glomulin/ALF4 | YAP-binding/ALF4/Glomulin |
|---|---|---|---|---|
| UniProtKB:Q5U3W2 | InterPro | 592 | ||
| UniProtKB:B0UYH7 | InterPro | 592 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-63K7 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7146372 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:101567 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192938 | ZFIN Curated Data |
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| Type | Accession # | Genome Assembly | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001007415 (1) | 2685 nt | ||
| Genomic | GenBank:CR450845 (1) | 232604 nt | ||
| Polypeptide | UniProtKB:B0UYH7 (1) | 592 aa |
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- Kuan, Y.S., Roberson, S., Akitake, C.M., Fortuno, L., Gamse, J., Moens, C., Halpern, M.E. (2015) Distinct requirements for Wntless in habenular development. Developmental Biology. 406(2):117-28
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
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- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
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