Gene
lpcat3
- ID
- ZDB-GENE-041111-232
- Name
- lysophosphatidylcholine acyltransferase 3
- Symbol
- lpcat3 Nomenclature History
- Previous Names
-
- im:7145298 (1)
- si:dkey-197a20.5
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable 1-acylglycerophosphocholine O-acyltransferase activity and lysophospholipid acyltransferase activity. Predicted to be involved in lipid modification; phosphatidylcholine biosynthetic process; and phosphatidylethanolamine acyl-chain remodeling. Predicted to act upstream of or within phospholipid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in membrane. Orthologous to human LPCAT3 (lysophosphatidylcholine acyltransferase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7145298 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Lysophospholipid acyltransferase 7/Porcupine-like | Membrane bound O-acyl transferase, MBOAT |
|---|---|---|---|---|
| UniProtKB:A0A8M6YSQ0 | InterPro | 466 | ||
| UniProtKB:E7FAX1 | InterPro | 465 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lpcat3-201
(1)
|
Ensembl | 3,042 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-26C10 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-197A20 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7145298 | Thisse et al., 2004 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001316738 (1) | 3040 nt | ||
| Genomic | GenBank:BX001019 (1) | 226271 nt | ||
| Polypeptide | UniProtKB:A0A8M6YSQ0 (1) | 466 aa |
- Liu, Q., Song, T., Chen, B., Zhang, J., Li, W. (2023) Ferroptosis of brain microvascular endothelial cells contributes to hypoxia-induced blood-brain barrier injury. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 37:e22874e22874
- Wang, Y., Bo, J., Zhao, Z., Han, Y., Zhang, Q., Liu, L. (2023) Depletion of Igfbp7 alleviates zebrafish NAFLD progression through inhibiting hepatic ferroptosis. Life sciences. 332:122086
- Petit, J., Bailey, E.C., Wheeler, R.T., de Oliveira, C.A.F., Forlenza, M., Wiegertjes, G.F. (2019) Studies Into β-Glucan Recognition in Fish Suggests a Key Role for the C-Type Lectin Pathway. Frontiers in immunology. 10:280
- Yoon, S., Mitra, S., Wyse, C., Alnabulsi, A., Zou, J., Weerdenburg, E.M., van der Sar, A.M., Wang, D., Secombes, C.J., Bird, S. (2015) First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio). PLoS One. 10:e0126378
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