Gene
mcat
- ID
- ZDB-GENE-041111-231
- Name
- malonyl CoA:ACP acyltransferase (mitochondrial)
- Symbol
- mcat Nomenclature History
- Previous Names
-
- im:7145278
- si:dkey-31f5.5
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable [acyl-carrier-protein] S-malonyltransferase activity. Predicted to be involved in fatty acid biosynthetic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human MCAT (malonyl-CoA-acyl carrier protein transacylase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7145278 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Optic atrophy 15 | 620583 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR014043 | Acyl transferase domain |
| Family | IPR052760 | Mitochondrial malonyltransferase |
| Homologous_superfamily | IPR001227 | Acyl transferase domain superfamily |
| Homologous_superfamily | IPR016035 | Acyl transferase/acyl hydrolase/lysophospholipase |
| Homologous_superfamily | IPR016036 | Malonyl-CoA ACP transacylase, ACP-binding |
Domain Details Per Protein
| Protein | Additional Resources | Length | Acyl transferase/acyl hydrolase/lysophospholipase | Acyl transferase domain | Acyl transferase domain superfamily | Malonyl-CoA ACP transacylase, ACP-binding | Mitochondrial malonyltransferase |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q5RGV8 | InterPro | 364 |
Interactions and Pathways
No data available
Plasmids
No data available