Gene
neb
- ID
- ZDB-GENE-041111-216
- Name
- nebulin
- Symbol
- neb Nomenclature History
- Previous Names
-
- im:6904860
- im:7001777
- im:7144538
- im:7150492
- si:ch211-168m7.5
- wu:fc33b04
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity. Involved in locomotion. Acts upstream of or within regulation of sarcomere organization and sarcomere organization. Predicted to be located in cytoplasm. Predicted to be active in Z disc. Is expressed in adaxial cell; heart; musculature system; pectoral fin; and somite. Used to study nemaline myopathy. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-6 and nemaline myopathy 2. Orthologous to human NEB (nebulin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 28 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144538 (1 image)
- IMAGE:6904860 (38 images)
- IMAGE:7150492 (10 images)
- IMAGE:7152889 (12 images)
- IMAGE:7162426 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- 23 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
arthrogryposis multiplex congenita-6 | Alliance | Arthrogryposis multiplex congenita 6 | 619334 |
nemaline myopathy 2 | Alliance | Nemaline myopathy 2, autosomal recessive | 256030 |
Domain, Family, and Site Summary
Domain Details Per Protein
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
neb-201
(1)
|
Ensembl | 1,431 nt | ||
mRNA |
neb-206
(1)
|
Ensembl | 523 nt | ||
mRNA |
neb-207
(1)
|
Ensembl | 2,133 nt | ||
mRNA |
neb-208
(1)
|
Ensembl | 19,401 nt | ||
mRNA |
neb-209
(1)
|
Ensembl | 1,163 nt | ||
ncRNA |
neb-003
(1)
|
Ensembl | 459 nt | ||
ncRNA |
neb-004
(1)
|
Ensembl | 639 nt | ||
ncRNA |
neb-005
(1)
|
Ensembl | 763 nt | ||
ncRNA |
neb-008
(1)
|
Ensembl | 826 nt |
Interactions and Pathways
No data available
Plasmids
No data available