Gene
inpp5f
- ID
- ZDB-GENE-041111-194
- Name
- inositol polyphosphate-5-phosphatase F
- Symbol
- inpp5f Nomenclature History
- Previous Names
-
- im:7143897 (1)
- si:dkey-192p21.1
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable inositol monophosphate 4-phosphatase activity; phosphatidylinositol-4-phosphate phosphatase activity; and protein homodimerization activity. Predicted to be involved in clathrin-dependent endocytosis; phosphatidylinositol dephosphorylation; and regulation of endocytic recycling. Predicted to be located in recycling endosome. Predicted to be active in clathrin-coated endocytic vesicle and early endosome. Orthologous to human INPP5F (inositol polyphosphate-5-phosphatase F).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7143897 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa8676 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa9903 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa18211 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa22302 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa22303 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa22304 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa35491 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa38941 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | hSac2 domain | Inositol phosphatase | SAC domain |
|---|---|---|---|---|---|
| UniProtKB:A8E7C5 | InterPro | ||||
| UniProtKB:A0A8M2B383 | InterPro | 1126 |
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- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
inpp5f-201
(1)
|
Ensembl | 3,363 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
- England, S.J., Campbell, P.C., Banerjee, S., Swanson, A.J., Lewis, K.E. (2017) Identification and Expression Analysis of the Complete Family of Zebrafish pkd Genes.. Frontiers in cell and developmental biology. 5:5
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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