snip1

ID

ZDB-GENE-041026-3

Name

Smad nuclear interacting protein

Symbol

snip1 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable mRNA binding activity. Acts upstream of or within mRNA splicing, via spliceosome. Predicted to be part of spliceosomal complex. Predicted to be active in nucleus. Is expressed in several structures, including blastodisc; fourth ventricle; notochord; otic vesicle; and pectoral fin bud. Orthologous to human SNIP1 (Smad nuclear interacting protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:114106 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Fernandez et al., 2018
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With snip1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with hypotonia, craniofacial abnormalities, and seizures	614501

Associated With snip1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000253	Forkhead-associated (FHA) domain
Family	IPR050923	Cellular Process Regulator and RNA Processing Protein
Homologous_superfamily	IPR008984	SMAD/FHA domain superfamily