Gene

snip1

ID

ZDB-GENE-041026-3

Name

Smad nuclear interacting protein

Symbol

snip1 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable mRNA binding activity. Acts upstream of or within mRNA splicing, via spliceosome. Predicted to be active in nucleus. Is expressed in several structures, including blastodisc; fourth ventricle; notochord; otic vesicle; and pectoral fin bud. Orthologous to human SNIP1 (Smad nuclear interacting protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:114106 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Fernandez et al., 2018
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With snip1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with hypotonia, craniofacial abnormalities, and seizures	614501

1 - 1 of 1

Associated With snip1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000253	Forkhead-associated (FHA) domain
Family	IPR050923	Cellular Process Regulator and RNA Processing Protein
Homologous_superfamily	IPR008984	SMAD/FHA domain superfamily

1 - 3 of 3

Domain Details Per Protein

Protein	Additional Resources	Length	Cellular Process Regulator and RNA Processing Protein	Forkhead-associated (FHA) domain	SMAD/FHA domain superfamily
UniProtKB:Q4V8W8	InterPro	374

1 - 1 of 1

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	snip1-201 (1) Ensembl	Ensembl		1,776 nt	Select Tool ZFIN BLAST
mRNA	snip1-202 (1) Ensembl	Ensembl		804 nt	Select Tool ZFIN BLAST

1 - 2 of 2

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	CH211-15N24	CR524825	ZFIN Curated Data
Contained in	BAC	CH211-134G22	BX649265	ZFIN Curated Data
Encodes	EST	fc58g10	AI878279	ZFIN Curated Data
Encodes	cDNA	MGC:114106	BC097166	ZFIN Curated Data

1 - 4 of 4

Show

Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_001025470 (1)	1792 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX649265 (1)	174317 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q4V8W8 (1)	374 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations

Include unpublished citations