Gene

prg4b

ID
ZDB-GENE-041014-324
Name
proteoglycan 4b
Symbol
prg4b Nomenclature History
Previous Names
  • prg4
  • si:dkey-97o5.3
  • zgc:122988
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have metal ion binding activity; polysaccharide binding activity; and scavenger receptor activity. Predicted to be involved in immune response. Is expressed in articular cartilage; inter-coracoid joint; liver; and quadrate-anguloarticular joint. Human ortholog(s) of this gene implicated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome and pericarditis. Orthologous to human PRG4 (proteoglycan 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Askary et al., 2016
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prg4b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
camptodactyly-arthropathy-coxa vara-pericarditis syndrome Alliance Camptodactyly-arthropathy-coxa vara-pericarditis syndrome 208250
Associated With prg4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018486 Hemopexin, conserved site
Domain IPR000585 Hemopexin-like domain
Domain IPR001212 Somatomedin B domain
Homologous_superfamily IPR036024 Somatomedin B-like domain superfamily
Homologous_superfamily IPR036375 Hemopexin-like domain superfamily
Repeat IPR018487 Hemopexin-like repeats
Domain Details Per Protein
Protein Length Hemopexin, conserved site Hemopexin-like domain Hemopexin-like domain superfamily Hemopexin-like repeats Somatomedin B domain Somatomedin B-like domain superfamily
UniProtKB:Q567C4 252
UniProtKB:A5PMB6 115
UniProtKB:F1REF9 711
UniProtKB:Q32PL6 408
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations